FAQs

What You Want and Need to Know about Nexafed

What is Nexafed?

Nexafed is the next-generation pseudoephedrine hydrochloride (HCl) nonprescription medication that combines effective nasal and sinus congestion relief with methamphetamine-resistant Impede® technology. Impede is a combination of safe inactive ingredients that disrupts the conversion of pseudoephedrine into the dangerous illegal drug methamphetamine, commonly known as meth.1

What is the active ingredient in Nexafed?

The active ingredient in Nexafed is pseudoephedrine HCl, which relieves nasal congestion due to the common cold, hay fever or other upper respiratory allergies. Nexafed also helps to decongest sinus openings and passages to temporarily relieve sinus congestion and pressure. Of pharmacists surveyed, 93% believed pseudoephedrine HCl is the most effective nasal decongestant available.1

What are the dosing instructions for Nexafed?

Nexafed may be taken every 4 to 6 hours, but not to exceed 4 doses in 24 hours. Take tablets with enough water to ensure complete swallowing immediately after placing in the mouth.

Adults and children 12 years and over Take 2 tablets every 4 to 6 hours
Children ages 6 to 11 years Take 1 tablet every 4 to 6 hours
Children under 6 years Ask a doctor

What are the available forms of Nexafed?

Nexafed is available in tablet form.

Is Nexafed available as an extended-relief formula?

Nexafed is currently available as an immediate-release tablet that can be taken every 4 to 6 hours. Do not exceed 4 doses in 24 hours.

Where can I purchase Nexafed?

Nexafed can be found behind the pharmacy or service counter at select stores. Talk to your pharmacist for more information.

How much does Nexafed cost?

Nexafed should be priced comparably to other name-brand pseudoephedrine HCl products.

What are the potential side effects of Nexafed?

Nexafed labeling lists the following warnings related to potential side effects:
  • If nervousness, dizziness, or sleeplessness occurs, discontinue use and consult a doctor.
  • If symptoms do not improve within 7 days or are accompanied by a fever, consult a doctor.
  • Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug.
  • Do not take this product if you have heart disease, high blood pressure, thyroid disease, diabetes, trouble urinating due to an enlarged prostate gland unless directed by a doctor.
  • If pregnant or breast-feeding, ask a health professional before use.
  • Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

What are the dosing instructions for children?

The dosing instructions for children ages 6 to under 12 years old is one tablet every 4 to 6 hours but not more than 4 doses in 24 hours. Tablets should be taken with enough water to ensure complete swallowing immediately after placing in the mouth.

Parents should ask a doctor before giving Nexafed to children under 6 years old.

Is the product safe for children?

The dosing instructions for children ages 6 to under 12 years old is one tablet every 4 to 6 hours but not more than 4 doses in 24 hours.

Parents should ask a doctor before giving Nexafed to children under 6 years old.

Is Nexafed effective in relieving cold and allergy congestion?

Nexafed is just as effective as other pseudoephedrine products on the market at relieving nasal congestion due to the common cold, hay fever or other upper respiratory allergies.1 A clinical study showed that the rate and extent of absorption and oral bioavailability of Nexafed pseudoephedrine HCI (2 x 30 mg) tablets with Impede were comparable to an equivalent oral dose of Sudafed® (a registered trademark and product of Johnson & Johnson) tablets.

How is Nexafed different from other pseudoephedrine products?

Developed by Acura Pharmaceuticals, Nexafed is the next-generation pseudoephedrine HCl product combining effective nasal congestion relief with a unique technology to disrupt the conversion of pseudoephedrine to the illegal drug methamphetamine.

Unlike other pseudoephedrine HCl products, Nexafed utilizes Acura’s Impede technology, a unique polymer matrix that incorporates inactive ingredients to form a thick gel that disrupts the extraction and conversion of pseudoephedrine to methamphetamine.1

Are the inactive ingredients in Impede® and Nexafed safe?

Yes. All ingredients in Nexafed with Impede technology are present in amounts comparable to those used in other pharmaceutical products approved by the FDA.5 Impede technology combines these ingredients in a unique way to give the medication its meth-resistant properties while maintaining the effectiveness of the active ingredient that the consumer expects for relief of nasal congestion due to the common cold, hay fever or other upper respiratory allergies.1

Is Nexafed FDA approved?

FDA regulations (the OTC Monograph) authorize the sale of Nexafed and other nonprescription pseudoephedrine products.5

Why is pseudoephedrine used to make methamphetamine?

Meth producers use a few chemical processing steps to convert the drug pseudoephedrine to the illegal drug methamphetamine. Because pseudoephedrine is available in many cold and allergy medicines, meth producers have easy access to this source material.